Title: Postdoctoral Fellow

Salary: $73,588

Department: Microbiology

Physical work location: 1468 Madison Avenue, New York, New York 10029

Name PI or Supervisor: Gustavo Palacios

Web link to Department: https://icahn.mssm.edu/about/departments/microbiology

Administrative Contact: Molly Deroy, molly.deroy@mssm.edu

Details of Research Project:

The Palacios Laboratory is seeking a motivated Postdoctoral Researcher to join a dynamic, collaborative research team working on identifying and characterizing critical virus-host interactions to support broad-spectrum antiviral development. This initiative focuses on mapping interactions essential for viral life cycles, aiming to understand and inhibit viral entry, replication, immune evasion, and release.

Responsibilities

Key Responsibilities:

1. Experimental Design & Implementation

• Conduct multi-omics analyses, including quantitative proteomics, to characterize virus-host protein interactions and study host factors involved in key viral processes.
• Perform virological assays under BSL-2 and BSL-3 conditions, managing studies with viral species relevant to pandemic potential.

2. Data Analysis & Integration

• Integrate multi-omics datasets (e.g., proteomics, transcriptomics) to map essential virus-host interactions.
• Collaborate with computational biology teams to support AI/ML-driven analyses for identifying critical viral and host targets.

3. Project Management & Collaboration

• Work closely with teams at ISMMS and partnering institutions, coordinating experiments, sharing data, and aligning research efforts.
• Participate in cross-functional meetings to report progress, address challenges, and contribute to strategy discussions.

4. Publication & Presentation

• Prepare and publish research findings in high-impact scientific journals.
• Present research at conferences and review meetings, highlighting advancements in host-pathogen interaction research and antiviral discovery.

Technical Duties:

• Flow-cytometry
• ELISA
• WB
• ELISPOT
• qPCR
• CyTOF data analyses
• Mouse work

Qualifications

Educational and other Requirements for the position:

• PhD in Virology, Immunology, Microbiology, or a related field.
• Expertise in virology, with hands-on experience in viral culture and host-pathogen interaction studies.
• Proficiency in multi-omics techniques, including proteomics and transcriptomics, with data analysis experience.
• Familiarity with BSL-2 and BSL-3 laboratory practices.
• Strong communication skills and the ability to work within a multidisciplinary team.

Experience Required: MD or PhD

SPOC-UAW Local 4100 at Icahn School of Medicine (Post Docs), 815 - Microbiology - ISM, Icahn School of Medicine

Strength through Unity and Inclusion

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About the Mount Sinai Health System:

Mount Sinai Health System is one of the largest academic medical systems in the New York metro area, with more than 48,000 employees working across eight hospitals, more than 400 outpatient practices, more than 300 labs, a school of nursing, and a leading school of medicine and graduate education. Mount Sinai advances health for all people, everywhere, by taking on the most complex health care challenges of our time — discovering and applying new scientific learning and knowledge; developing safer, more effective treatments; educating the next generation of medical leaders and innovators; and supporting local communities by delivering high-quality care to all who need it. Through the integration of its hospitals, labs, and schools, Mount Sinai offers comprehensive health care solutions from birth through geriatrics, leveraging innovative approaches such as artificial intelligence and informatics while keeping patients’ medical and emotional needs at the center of all treatment. The Health System includes more than 9,000 primary and specialty care physicians; 13 joint-venture outpatient surgery centers throughout the five boroughs of New York City, Westchester, Long Island, and Florida; and more than 30 affiliated community health centers. We are consistently ranked by U.S. News & World Report's Best Hospitals, receiving high "Honor Roll" status, and are highly ranked: No. 1 in Geriatrics, top 5 in Cardiology/Heart Surgery, and top 20 in Diabetes/Endocrinology, Gastroenterology/GI Surgery, Neurology/Neurosurgery, Orthopedics, Pulmonology/Lung Surgery, Rehabilitation, and Urology. New York Eye and Ear Infirmary of Mount Sinai is ranked No. 12 in Ophthalmology. U.S. News & World Report’s “Best Children’s Hospitals” ranks Mount Sinai Kravis Children's Hospital among the country’s best in several pediatric specialties. The Icahn School of Medicine at Mount Sinai is ranked No. 11 nationwide in National Institutes of Health funding and in the 99th percentile in research dollars per investigator according to the Association of American Medical Colleges. Newsweek’s “The World’s Best Smart Hospitals” ranks The Mount Sinai Hospital as No. 1 in New York and in the top five globally, and Mount Sinai Morningside in the top 20 globally.

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