“Mineralys Therapeutics is a clinical-stage biopharmaceutical company focused on developing medicines to target hypertension and related comorbidities such as chronic kidney disease (CKD), obstructive sleep apnea (OSA) and other diseases driven by dysregulated aldosterone. Its initial product candidate, lorundrostat, is a proprietary, orally administered, highly selective aldosterone synthase inhibitor. Mineralys is headquartered in Radnor, Pennsylvania. For more information, please visit https://mineralystx.com. Follow Mineralys on LinkedIn, Twitter and Bluesky”

Mineralys is a fully remote company.

Regional Sales Director

The Regional Sales Director (RSD) will play a critical role in the successful launch and growth of Mineralys’ first commercial product within an assigned region. This leader will be accountable for translating national strategy into regional execution, driving business performance through strong field leadership, cross-functional partnership, and disciplined execution against launch objectives.

The RSD will build and lead a high-performing team of territory managers, foster deep customer relationships, and ensure alignment with corporate priorities, compliance standards, and Mineralys’ values. This is a highly visible field leadership role requiring strong business acumen, launch experience, and the ability to lead with urgency in a fast-paced, entrepreneurial environment.

The RSD will cover a Territory including:

• Pittsburgh, PA
• Harrisburg, PA
• Cleveland, OH
• Wheeling, WV
• Buffalo, NY

Key Responsibilities

Commercial Leadership / Launch Execution

• Lead all regional launch planning and execution activities to ensure successful market entry and sustained product uptake
• Translate national brand strategy into actionable regional business plans and field execution priorities
• Lead team to achieve or exceed sales goals, market share targets, and key performance metrics at launch and beyond
• Monitor market dynamics, customer feedback, and competitive intelligence to adjust strategy in real time
• Drive accountability for performance through data-driven decision making and disciplined execution

Team Leadership / Coaching

• Recruit, onboard, develop, and retain top-performing territory managers across the region
• Lead, coach, and motivate a team of approximately 8–12 territory managers
• Establish and maintain high level of disease state, clinical and product knowledge
• Evaluate performance of territory managers and coach to skill and career development through regular field contact
• Foster a high-performance culture focused on accountability, collaboration, and continuous improvement
• Build strong succession plans and talent pipelines

Customer / Market Engagement

• Develop and maintain relationships with key healthcare providers, health systems, integrated delivery networks (IDNs) and strategic accounts
• Partner with territory managers on key customer interactions, access challenges, and develop account strategies
• Support pull-through with IDNs, organized customers, and priority accounts
• timely and effectively sharing of customer insights with internal stakeholders

Cross-Functional Collaboration

• Partner closely with Market Access, Marketing, Medical Affairs, Training, Operations, and HR to support launch readiness and execution
• Provide field-driven input into brand planning, messaging, and tactical adjustments
• Collaborate with Area Sales Directors and peers to share best practices and drive consistency across regions
• Support national meetings, launch planning sessions, and field communications

Compliance / Operational Excellence

• Ensure all regional activities are conducted in full compliance with company policies, industry regulations, and legal standards
• Manage regional budgets and resources effectively
• Maintain accurate forecasting, CRM utilization, and reporting discipline
• Uphold Mineralys’ values of collaboration, integrity, quality, trust, and urgency

Qualifications

• Bachelor’s degree required; advanced degree preferred
• 8+ years of pharmaceutical / biotech sales experience
• 3+ years of people leadership experience in a district / regional manager role
• Proven success leading specialty sales teams and exceeding performance goals
• Prior launch experience required; first-launch / startup biotech experience strongly preferred
• Experience in cardiovascular, nephrology, hypertension, or related specialty markets strongly preferred
• Demonstrated success in recruiting and developing top talent
• Strong business planning, analytical, and coaching skills
• Ability to work effectively in a fast-paced, highly collaborative environment
• Willingness to travel extensively within region

Leadership Profile

• A strong coach who develops people and builds winning teams
• Highly accountable, with a bias for action and urgency
• Comfortable operating in ambiguity and helping build infrastructure
• Collaborative and able to influence across functions
• Resilient, adaptable, and energized by launch environments

Travel

• This position requires up to 60% travel. Frequently travel is outside the local area and overnight.

These positions are eligible for standard Company benefits including medical, dental, vision, time off and 401K, as well as participating in Mineralys incentive plans are contingent on achievement of personal and company performance. Actual compensation may vary from posted hiring range based on geographic location, work experience, education, and/or skill level.

US Salary Range: $180,000 - $215,000

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