Use Your Power for Purpose

This position is for a Clinical Development Medical Executive Director supporting Thoracic Cancers. The Clinical Development Medical Executive Director will be responsible for defining and executing on the development strategy of oncology program(s). Reporting to the Global Development Product Lead, the successful candidate should have demonstrated proficiency in leading and/or supporting development programs, cross-functional collaboration, and represent program(s) externally.

This position will be responsible for supporting leading one or more subteams in clinical development and/or serving as the clinical lead across multiple clinical trials. The successful candidate should ideally have prior experience in clinical trials, supporting development programs, health authority interactions and demonstrated leadership capabilities.

What You Will Achieve

Clinical Development Medical Executive Director Responsibilities

• May lead product specific Global Development Team (GDT) 
• Serves as the subject matter expert on clinical issues 
• Work across the organization and on the cross-functional Global Development Team to lead, develop and execute the clinical development plan of one or more indications in alignment with the Lifecycle Management Plan and Integrated Product Plan 
• Endorses clinical decisions in advance of Global Product team (GPT), senior management reviews or governance bodies with the Global Development Product Lead (GDPL) 
• May provide oversight and management responsibilities of medical director(s) 
• Accountable for the clinical development strategy, trial design, execution, and delivery of trial results with the GDPL 
• Accountable for integrating regulatory, statistical and other internal and external stakeholder input into study designs 
• Serves as primary interface with Development Review Committee 
• Oversee the development and management of clinical protocols and amendments, investigator brochures, and clinical study reports 
• Oversee the evaluation, interpretation, reporting and presentation of study data 
• Accountable with safety for clinical evaluations and safety decisions, escalating to GDPL as necessary 
• Accountable with clinical pharmacology for defining and identifying optimal dose and schedule selection  
• Accountable with regulatory for health authority interactions, escalating to GDPL as necessary 
• May participate in evaluating business development opportunities 
• Conduct medical monitoring activities including eligibility assessment, data review and safety monitoring 
• Lead peer-to-peer interactions with investigator 
• Serve as the point of contact for clinical issues between the study team, investigators, ethics committees, steering committees, and regulatory authorities 
• Lead and contribute to development and maintenance of clinical trial and regulatory documents, in collaboration with Clinical Scientist and the cross-functional team 
• Oversee and provide clinical development leadership across several study teams 
• Serves as the Clinical Development Lead on working groups and subteams including for Marketing Authorization Applications and in business development opportunities 

Strategic Guidance, Clinical Insights & Interpretation

• Lead, develop and execute the strategic development of therapies for one or multiple medicines in designated therapeutic area, collaborating with the GDPL as needed 
• Represents the company in external engagements or in as committee members in joint collaborations 
• Collaborate with Clinical Scientist to review and interpret clinical data, identify key findings and implications, and communicate to internal and external stakeholders 
• Maintains a high level of clinical expertise and professional competence by staying abreast of the latest developments, literature, and guidelines to advise on and drive current and future clinical development plans 

 What You Wil Need (BASIC QUALIFICATIONS)

• Medical degree or advanced degree with relevant clinical/industry experience (typically 5+ years). 
• Been licensed/registered by a medical licensing authority to prescribe medicines independent of Supervision for at least two years
• 5+ years of experience leading diverse teams 
• Prior management responsibilities of medical directors or clinical scientists 
• Late phase drug development experience.

Bonus To Have (PREFERRED QUALIFICATIONS)

• Board certified/eligible in oncology or equivalent 
• Experience treating and/or leading trials in thoracic cancer therapeutic area
• Experience treating and/or immunooncology leading trials
• Experience across multiple phases of clinical development and across drug classes in oncology 
• Experience in leading NDA, BLA or MAA

Candidate demonstrates a breadth of diverse leadership experiences and capabilities including: the ability to influence and collaborate with peers, develop and coach others, oversee and guide the work of other colleagues to achieve meaningful outcomes and create business impact.

Relocation support available

Work Location Assignment: This is a hybrid role requiring you to live within commuting distance and work on-site an average of 2.5 days per week.


The annual base salary for this position ranges from $295,900.00 to $493,100.00. In addition, this position is eligible for participation in Pfizer’s Global Performance Plan with a bonus target of 30.0% of the base salary and eligibility to participate in our share based long term incentive program. We offer comprehensive and generous benefits and programs to help our colleagues lead healthy lives and to support each of life’s moments. Benefits offered include a 401(k) plan with Pfizer Matching Contributions and an additional Pfizer Retirement Savings Contribution, paid vacation, holiday and personal days, paid caregiver/parental and medical leave, and health benefits to include medical, prescription drug, dental and vision coverage. Learn more at Pfizer Candidate Site – U.S. Benefits | (uscandidates.mypfizerbenefits.com). Pfizer compensation structures and benefit packages are aligned based on the location of hire. The United States salary range provided does not apply to Tampa, FL or any location outside of the United States.



This role is posted in multiple locations. If you are applying for the role in an secondary job posting location where pay transparency regulations apply, your Talent Advisor will share the local pay information with you during the first interview.




Relocation assistance may be available based on business needs and/or eligibility.




Candidates must be authorized to be employed in the U.S. by any employer.

U.S. work visa sponsorship (such as TN, O-1, H-1B, etc.) is not available for this role now or in the future.




Sunshine Act

Pfizer reports payments and other transfers of value to health care providers as required by federal and state transparency laws and implementing regulations.  These laws and regulations require Pfizer to provide government agencies with information such as a health care provider’s name, address and the type of payments or other value received, generally for public disclosure.  Subject to further legal review and statutory or regulatory clarification, which Pfizer intends to pursue, reimbursement of recruiting expenses for licensed physicians may constitute a reportable transfer of value under the federal transparency law commonly known as the Sunshine Act.  Therefore, if you are a licensed physician who incurs recruiting expenses as a result of interviewing with Pfizer that we pay or reimburse, your name, address and the amount of payments made currently will be reported to the government.  If you have questions regarding this matter, please do not hesitate to contact your Talent Acquisition representative.




EEO & Employment Eligibility

Pfizer is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status.  Pfizer also complies with all applicable national, state and local laws governing nondiscrimination in employment as well as work authorization and employment eligibility verification requirements of the Immigration and Nationality Act and IRCA.  Pfizer is an E-Verify employer.  This position requires permanent work authorization in the United States.

Pfizer endeavors to make www.pfizer.com/careers accessible to all users. If you would like to contact us regarding the accessibility of our website or need assistance completing the application process and/or interviewing, please email disabilityrecruitment@pfizer.com. This is to be used solely for accommodation requests with respect to the accessibility of our website, online application process and/or interviewing. Requests for any other reason will not be returned.




To learn more about acceptable and prohibited uses of AI during the recruitment process, please review our candidate AI-use guidelines available on Pfizer Careers.


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